Lacosamide

PharmAlliance International Labs introduces Lacosamide Tablets for treating partial-onset seizures in patients 17 years and older with epilepsy. Classified as an antiepileptic drug, lacosamide stabilizes neuronal membranes and reduces hyperexcitability by enhancing the slow inactivation of voltage-gated sodium channels. Available in 50mg and 100mg strengths, the tablets are administered twice daily, starting at 50mg and potentially increasing to 400mg per day, with adjustments for renal or hepatic impairments. Lacosamide is rapidly absorbed, minimally metabolized, and primarily excreted in urine, with a half-life of 13 hours. Common side effects include dizziness and nausea, with rare serious adverse events like cardiac abnormalities.

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Description

Introducing Lacosamide Tablets by PharmAlliance International Labs

Welcome to PharmAlliance International Labs, where we are dedicated to advancing healthcare by providing innovative pharmaceutical solutions. Our Lacosamide Tablets offer effective treatment for various neurological conditions, enhancing patients’ quality of life and well-being.

Drug Classification:

Lacosamide belongs to the class of medications known as antiepileptic drugs (AEDs). It works by stabilizing neuronal membranes and reducing the hyperexcitability of neurons, thereby exerting anticonvulsant effects. Lacosamide is indicated for the management of partial-onset seizures in adults and adolescents with epilepsy.

Formulations:

Lacosamide Tablets:

  • Strength: Available in 50mg and 100mg tablets.
  • Product Form: Oral tablets for convenient administration.
  • Packing Specs: Each pack contains 14 tablets.

Indications:

Lacosamide Tablets are indicated as adjunctive therapy for the treatment of partial-onset seizures in patients aged 17 years and older with epilepsy. Partial-onset seizures are characterized by abnormal electrical activity in a specific area of the brain, leading to transient alterations in behavior, consciousness, or sensory perception.

Usage:

Lacosamide Tablets should be taken orally with or without food, as directed by a healthcare provider. It is essential to follow the prescribed dosage regimen and treatment duration to achieve optimal seizure control. Lacosamide may be used alone or in combination with other antiepileptic medications, depending on individual patient response and treatment goals.

Dosage:

The recommended starting dosage of Lacosamide Tablets is 50mg twice daily, with a gradual titration based on individual patient response and tolerability. The maximum recommended dosage is 400mg per day, administered in two divided doses. Dosage adjustments may be necessary in patients with renal impairment or hepatic dysfunction.

Pharmacokinetics:

Lacosamide is rapidly and extensively absorbed following oral administration, with peak plasma concentrations reached within 1 to 4 hours. It undergoes minimal metabolism in the liver, primarily via hydrolysis, and is predominantly excreted unchanged in the urine. The elimination half-life of lacosamide is approximately 13 hours, allowing for twice-daily dosing.

Pharmacodynamics:

Lacosamide exerts its pharmacological effects by selectively enhancing the slow inactivation of voltage-gated sodium channels in neurons, thereby reducing neuronal excitability and inhibiting abnormal electrical activity. By modulating sodium channel activity, lacosamide helps stabilize neuronal membranes and suppresses the spread of epileptic discharges, resulting in seizure control.

Side Effects:

Common side effects of Lacosamide Tablets may include dizziness, headache, nausea, vomiting, fatigue, and diplopia (double vision). Less frequently observed adverse reactions may include somnolence, ataxia, tremor, and blurred vision. Serious adverse events, such as cardiac conduction abnormalities or allergic reactions, are rare but may occur.

Trust in the efficacy and safety of Lacosamide Tablets from PharmAlliance International Labs. We are committed to supporting patients with epilepsy and providing them with the necessary treatment options to manage their condition effectively. For more information, please visit our website or consult your healthcare provider.

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